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03705nam a22005055i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310153326.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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130507s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781441978622 |
|
978-1-4419-7862-2 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QD96.M3 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
543.65 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Boston, MA : |
| -- |
Springer US : |
| -- |
Imprint: Springer, |
| -- |
2013. |
| 912 ## - |
|---|
| -- |
ZDB-2-CMS |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Chen, Guodong. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Characterization of Protein Therapeutics using Mass Spectrometry |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Guodong Chen. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
X, 404 p. 148 illus., 38 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Characterization of Protein Therapeutics by Mass Spectrometry: Recent Developments and Future Directions -- The Use of Mass Spectrometry to Characterize the Metabolism of Peptide Therapeutics -- Quantitative Analysis of Biologics Using Mass Spectrometry -- Maximizing Structural Information from Whole Protein Tandem Mass Spectrometry -- Disulfide Linkages of an Albumin Fusion Protein -- Detailed Structural Characterization of Monoclonal Antibodies -- Application of Protein Mass Spectrometry in Impurity and Degradant Characterization -- Mass Spectrometry Methods to Analyze Higher Order Structure of Protein Therapeutics by Chemical Footprinting -- Aglycosylations Alters Protein Conformation in Antibodies Engineered with Specific Effector Functions Using HDX-MS -- Characterizing Biotherapeutic Protein 3D Structures by Electrospray Ion-Mobility Mass Spectrometry -- Oxford University, Characterization of Assemblies of Proteins by Mass Spectrometry. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Protein therapeutics’ high efficacy, safety, and ability to treat life-threatening diseases such as cancer, inflammation and genetic disorders have revolutionized modern medicine. In 2012, 200 companies competed in this $90 billion year industry. In Characterization of Protein Therapeutics using Mass Spectrometry, expert contributors from academia and industry highlight current approaches and future trends. The book discusses mass spectrometry techniques as related to the analysis of protein therapeutics, structural identification strategies and quantitative approaches. The book also covers various studies involving characterization of process related protein drug impurities/degradants, metabolites, PTMs and higher order structures of protein therapeutics. General practitioners in pharmaceutical research, specialists in analytical sciences, and graduate students studying mass spectrometry and pharmaceutical sciences will find this book useful because of the step-by-step approaches and new strategies to solve challenging problems related to protein therapeutics research and development. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Chemistry. |
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|---|
| Topical term or geographic name as entry element |
Human genetics. |
|
|---|
| Topical term or geographic name as entry element |
Pharmaceutical technology. |
|
|---|
| Topical term or geographic name as entry element |
Mass spectrometry. |
|
|---|
| Topical term or geographic name as entry element |
Biotechnology. |
|
|---|
| Topical term or geographic name as entry element |
Biochemistry. |
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|---|
| Topical term or geographic name as entry element |
Surfaces (Physics). |
|
|---|
| Topical term or geographic name as entry element |
Chemistry. |
|
|---|
| Topical term or geographic name as entry element |
Mass Spectrometry. |
|
|---|
| Topical term or geographic name as entry element |
Protein Science. |
|
|---|
| Topical term or geographic name as entry element |
Pharmaceutical Sciences/Technology. |
|
|---|
| Topical term or geographic name as entry element |
Biotechnology. |
|
|---|
| Topical term or geographic name as entry element |
Human Genetics. |
|
|---|
| Topical term or geographic name as entry element |
Characterization and Evaluation of Materials. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781441978615 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-7862-2 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
