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03321nam a22004815i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310153327.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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110406s2011 au | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783211990797 |
|
978-3-211-99079-7 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QD146-197 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
546 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Vienna : |
| -- |
Springer Vienna : |
| -- |
Imprint: Springer, |
| -- |
2011. |
| 912 ## - |
|---|
| -- |
ZDB-2-CMS |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Aldrich-Wright, Janice. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Metallointercalators |
| Medium |
[electronic resource] : |
| Remainder of title |
Synthesis and Techniques to Probe Their Interactions with Biomolecules / |
| Statement of responsibility, etc |
edited by Janice Aldrich-Wright. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XXVIII, 427p. 120 illus., 40 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Introduction -- Synthesis:Platinum Intercalating Complexes; Binuclear Platinum Complexes;Binuclear Ruthenium and Platinum Intercalating Complexes; Sequence Selective Intercalating Complexes; Targeting and Improving Transport, Cucurbit[n]uril, Cylcodextrin and Dendrimers -- Techniques to Probe Interactions with Biomolecules:Introduction to NMR; DNA-NMR; PGSE-NMR; DNA ESI-MS; Investigating Binding Interactions using Linear Dichromism and Circular Dichromism; Flourescence Spectroscopy; Confocal Microscopy; Implementation of synchotron X-ray microscopy for investigations of the cellular uptake and cellular metabolism of metallointercalators; Biomolecular Helical Structure; Viscosity, TGA and Dialysis; Microarrays; Cytotoxicity-Cell lines; Antibacterical activity; Animal testing. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confocal Microscopy, Viscosity, TGA and dialysis, Microarrays, biological analysis. Chapters are devoted to the synthesis and the techniques used to study the interactions of inorganic complexes with biomolecules. Considerably detailed examples are used to help illustrate the application of these techniques. This book is a useful resource for an array of inorganic and organic advanced undergraduate and graduate courses and for researchers in drug discovery. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Chemistry. |
|
|---|
| Topical term or geographic name as entry element |
Spectroscopy. |
|
|---|
| Topical term or geographic name as entry element |
Chemistry, inorganic. |
|
|---|
| Topical term or geographic name as entry element |
Chemistry, Physical organic. |
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| Topical term or geographic name as entry element |
Pharmacy. |
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|---|
| Topical term or geographic name as entry element |
Biochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Chemistry. |
|
|---|
| Topical term or geographic name as entry element |
Inorganic Chemistry. |
|
|---|
| Topical term or geographic name as entry element |
Pharmacy. |
|
|---|
| Topical term or geographic name as entry element |
Biochemistry, general. |
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|---|
| Topical term or geographic name as entry element |
Physical Chemistry. |
|
|---|
| Topical term or geographic name as entry element |
Spectroscopy/Spectrometry. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9783211094273 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-211-99079-7 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
