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Drug Discovery in Africa (Record no. 27918)

000 -LEADER
fixed length control field 04598nam a22004695i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310153332.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120808s2012 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783642281754
978-3-642-28175-4
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RS400-431
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615.19
Edition number 23
264 #1 -
-- Berlin, Heidelberg :
-- Springer Berlin Heidelberg :
-- Imprint: Springer,
-- 2012.
912 ## -
-- ZDB-2-CMS
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Chibale, Kelly.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Drug Discovery in Africa
Medium [electronic resource] :
Remainder of title Impacts of Genomics, Natural Products, Traditional Medicines, Insights into Medicinal Chemistry, and Technology Platforms in Pursuit of New Drugs /
Statement of responsibility, etc edited by Kelly Chibale, Mike Davies-Coleman, Collen Masimirembwa.
300 ## - PHYSICAL DESCRIPTION
Extent XX, 438 p. 102 illus., 3 illus. in color.
Other physical details online resource.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Overview of Current Drug Discovery Activities in Africa and Their Links to International Efforts to Combat Tropical Infectious Diseases -- The National Cancer Institute and Natural Product Based Drug Discovery in Africa -- Tuberculosis Drug Discovery: Target Identification and Validation -- Targeting Conserved Pathways as a Strategy for Novel Drug Development: Disabling the Cellular Stress Response -- Natural Product-Based Drug Discovery in Africa: The Need for Integration into Modern Drug-Discovery Paradigms -- Searching for Drugs that Target Multiple Receptors for Anthelmintics from African Natural Products -- Application of in silico, in vitro and in vivo ADMET/PK Platforms in Drug Discovery -- Marine Bioprospecting in Southern Africa -- Natural Products-Based Drug Discovery against Neglected Diseases with Special Reference to African Natural Resources -- ‘Now I heal with pride’ - The Application of Screens-to-Nature (STN) Technology to Indigenous Knowledge Systems Research in Botswana: Implications for Drug Discovery -- Innovative Approaches to Exploiting Traditional Medicines in Malaria -- Anticancer Drug Repositioning against Tropical Diseases: The Example of Methotrexate in the Treatment of Malaria -- Tackling the Problem of Antimalarial Resistance -- Random and Rational Approaches to HIV Drug Discovery in Africa -- Structure-Based Design of Domain-Selective Angiotensin-Converting Enzyme Inhibitors -- Natural Products and Antimalarial Drugs. Will Africa Provide the Next Major Breakthrough? -- Nanomedicine in the Development of Drugs for Poverty Related Diseases.
520 ## - SUMMARY, ETC.
Summary, etc Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. Compiled by leading African and international experts, this book presents the science and strategies of modern drug discovery. It explores how the use of natural products and traditional medicines can benefit from conventional drug discovery approaches, and proposes solutions to current technological, infrastructural, human resources, and economic challenges, which are presented when attempting to engage in full-scale drug discovery. Topics addressed are varied; from African medicinal plants to marine bioprospecting, pharmacogenetics and the use of nanotechnology. This book brings together for the first time a collection of strategies and techniques that need to be considered when developing drugs in an African setting. It is an unprecedented and truly international effort, highlighting the remarkable effort made so far in the area of drug discovery research by African scientists, and scientists from other parts of the world working on African health problems.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Chemistry.
Topical term or geographic name as entry element Chemistry, Organic.
Topical term or geographic name as entry element Biochemistry.
Topical term or geographic name as entry element Pharmacy.
Topical term or geographic name as entry element Chemistry.
Topical term or geographic name as entry element Medicinal Chemistry.
Topical term or geographic name as entry element Organic Chemistry.
Topical term or geographic name as entry element Pharmacy.
Topical term or geographic name as entry element Medical Biochemistry.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Davies-Coleman, Mike.
Relator term editor.
Personal name Masimirembwa, Collen.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9783642281747
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-642-28175-4
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-14AUM Main Library2014-04-14 2014-04-14 E-Book   AUM Main Library615.19