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Protein kinases as drug targets /

Authors: Klebl, Bert.%editor | Hamacher, Michael.%editor | %Muller, Gerhard,%1963-%editor Series: Methods and principles in medicinal chemistry ; . v. 49. Published by : Wiley-VCH ; (Weinheim :) Physical details: xxi, 373 p. : ill. (some col.) ; 25 cm. ISBN: 3527317902 Subject(s): Protein Kinase Inhibitors %therapeutic use. | Drug delivery systems. | Drug Discovery. | Protein kinases %Inhibitors. | Antineoplastic agents %Development. Year: 2011
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Item type Location Call Number Status Notes Date Due
Book Book AUM Main Library 615.798 P76 (Browse Shelf) Available JBC/2011/11262
Book Book AUM Main Library 615.798 P76 (Browse Shelf) Available JBC/2011/11262

Includes bibliographical references and index.

In vitro characterization of small-molecule kinase inhibitors -- Screening for kinase inhibitors: from biochemical to cellular assays -- Dissecting phosphorylation networks: the use of analogue-sensitive kinases and more specific kinase inhibitors as tools -- Rational drug design of kinase inhibitors for signal transduction therapy -- Kinase inhibitors in signal transduction therapy -- Design principles of deep pocket-targeting protein kinase inhibitors -- From discovery to clinic: aurora kinase inhibitors as novel treatments for cancer -- Discovery and design of protein kinase inhibitors: targeting the cell cycle in oncology -- Medicinal chemistry approaches for the inhibition of the p38 MAPK pathway -- Cellular protein kinases as antiviral targets -- Prospects for TB therapeutics targeting mycobacterium tuberculosis phosphosignaling networks.

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