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E-Book E-Book AUM Main Library 005.1 (Browse Shelf) Not for loan

An Algorithmic Framework for Predicting Side-Effects of Drugs -- SubMAP: Aligning Metabolic Pathways with Subnetwork Mappings -- Admixture Aberration Analysis: Application to Mapping in Admixed Population Using Pooled DNA -- Pathway-Based Functional Analysis of Metagenomes -- Hierarchical Generative Biclustering for MicroRNA Expression Analysis -- Subnetwork State Functions Define Dysregulated Subnetworks in Cancer -- Proteome Coverage Prediction for Integrated Proteomics Datasets -- Discovering Regulatory Overlapping RNA Transcripts -- Alignment-Free Phylogenetic Reconstruction -- Inference of Isoforms from Short Sequence Reads -- The Clark Phase-able Sample Size Problem: Long-Range Phasing and Loss of Heterozygosity in GWAS -- A New Algorithm for Improving the Resolution of Cryo-EM Density Maps -- Towards Automated Structure-Based NMR Resonance Assignment -- Gapped Spectral Dictionaries and Their Applications for Database Searches of Tandem Mass Spectra -- naiveBayesCall: An Efficient Model-Based Base-Calling Algorithm for High-Throughput Sequencing -- Extracting Between-Pathway Models from E-MAP Interactions Using Expected Graph Compression -- Simultaneous Identification of Causal Genes and Dys-Regulated Pathways in Complex Diseases -- Incremental Signaling Pathway Modeling by Data Integration -- The Poisson Margin Test for Normalisation Free Significance Analysis of NGS Data -- Compressing Genomic Sequence Fragments Using SlimGene -- On the Genealogy of Asexual Diploids -- Genovo: De Novo Assembly for Metagenomes -- MoGUL: Detecting Common Insertions and Deletions in a Population -- Generalized Buneman Pruning for Inferring the Most Parsimonious Multi-state Phylogeny -- Seed Design Framework for Mapping SOLiD Reads -- Accurate Estimation of Expression Levels of Homologous Genes in RNA-seq Experiments -- Cactus Graphs for Genome Comparisons -- IDBA – A Practical Iterative de Bruijn Graph De Novo Assembler -- Predicting Nucleosome Positioning Using Multiple Evidence Tracks -- Dense Subgraphs with Restrictions and Applications to Gene Annotation Graphs -- Time and Space Efficient RNA-RNA Interaction Prediction via Sparse Folding -- HLA Type Inference via Haplotypes Identical by Descent -- Algorithms for Detecting Significantly Mutated Pathways in Cancer -- Leveraging Sequence Classification by Taxonomy-Based Multitask Learning -- A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l-Tuples -- A Markov Random Field Framework for Protein Side-Chain Resonance Assignment -- Genomic DNA k-mer Spectra: Models and Modalities -- Deciphering the Swine-Flu Pandemics of 1918 and 2009 -- Distinguishing Direct versus Indirect Transcription Factor-DNA Interactions -- A Self-regulatory System of Interlinked Signaling Feedback Loops Controls Mouse Limb Patterning -- Automated High-Dimensional Flow Cytometric Data Analysis -- Discovering Transcriptional Modules by Combined Analysis of Expression Profiles and Regulatory Sequences.

This book constitutes the refereed proceedings of the 14th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2010, held in Lisbon, Portugal, in April 2010. The 36 revised full papers were carefully reviewed and selected from 176 submissions. The papers cover all areas of computational molecular biology such as molecular sequence analysis; recognition of genes and regulatory elements; molecular evolution; gene expression; biological networks; sequencing and genotyping technologies; genomics; population genetics; systems biology; imaging; computational proteomics; and molecular structural biology.

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