Library of American University of Madaba
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Protein kinases as drug targets /
edited by Bert Klebl, Gerhard Muller, and Michael Hamacher.
- Weinheim : Wiley-VCH ; 2011.
- xxi, 373 p. : ill. (some col.) ; 25 cm.
- Methods and principles in medicinal chemistry ; v. 49. .
- Methods and principles in medicinal chemistry ; v. 49. .
Includes bibliographical references and index.
In vitro characterization of small-molecule kinase inhibitors -- Screening for kinase inhibitors: from biochemical to cellular assays -- Dissecting phosphorylation networks: the use of analogue-sensitive kinases and more specific kinase inhibitors as tools -- Rational drug design of kinase inhibitors for signal transduction therapy -- Kinase inhibitors in signal transduction therapy -- Design principles of deep pocket-targeting protein kinase inhibitors -- From discovery to clinic: aurora kinase inhibitors as novel treatments for cancer -- Discovery and design of protein kinase inhibitors: targeting the cell cycle in oncology -- Medicinal chemistry approaches for the inhibition of the p38 MAPK pathway -- Cellular protein kinases as antiviral targets -- Prospects for TB therapeutics targeting mycobacterium tuberculosis phosphosignaling networks.
9783527317905 (hbk. : alk. paper) 3527317902 (hbk. : alk. paper)
Protein Kinase Inhibitors--therapeutic use.
Drug delivery systems.
Drug Discovery.
Protein kinases--Inhibitors.
Antineoplastic agents--Development.
RM666.E548 / P76 2011
615.798 / P76
Includes bibliographical references and index.
In vitro characterization of small-molecule kinase inhibitors -- Screening for kinase inhibitors: from biochemical to cellular assays -- Dissecting phosphorylation networks: the use of analogue-sensitive kinases and more specific kinase inhibitors as tools -- Rational drug design of kinase inhibitors for signal transduction therapy -- Kinase inhibitors in signal transduction therapy -- Design principles of deep pocket-targeting protein kinase inhibitors -- From discovery to clinic: aurora kinase inhibitors as novel treatments for cancer -- Discovery and design of protein kinase inhibitors: targeting the cell cycle in oncology -- Medicinal chemistry approaches for the inhibition of the p38 MAPK pathway -- Cellular protein kinases as antiviral targets -- Prospects for TB therapeutics targeting mycobacterium tuberculosis phosphosignaling networks.
9783527317905 (hbk. : alk. paper) 3527317902 (hbk. : alk. paper)
Protein Kinase Inhibitors--therapeutic use.
Drug delivery systems.
Drug Discovery.
Protein kinases--Inhibitors.
Antineoplastic agents--Development.
RM666.E548 / P76 2011
615.798 / P76