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Phosphodiesterases as Drug Targets (Record no. 18010)

000 -LEADER
fixed length control field 02309nam a22005175i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150242.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 110621s2011 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783642179693
978-3-642-17969-3
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RM1-950
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615
Edition number 23
264 #1 -
-- Berlin, Heidelberg :
-- Springer Berlin Heidelberg,
-- 2011.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Francis, Sharron H.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Phosphodiesterases as Drug Targets
Medium [electronic resource] /
Statement of responsibility, etc edited by Sharron H. Francis, Marco Conti, Miles D. Houslay.
300 ## - PHYSICAL DESCRIPTION
Extent XVIII, 522 p.
Other physical details online resource.
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE
Title Handbook of Experimental Pharmacology,
International Standard Serial Number 0171-2004 ;
Volume number/sequential designation 204
520 ## - SUMMARY, ETC.
Summary, etc Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Toxicology.
Topical term or geographic name as entry element Biochemistry.
Topical term or geographic name as entry element Enzymes.
Topical term or geographic name as entry element Post-translational modification of proteins.
Topical term or geographic name as entry element Cytology.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Pharmacology/Toxicology.
Topical term or geographic name as entry element Medicinal Chemistry.
Topical term or geographic name as entry element Protein Structure.
Topical term or geographic name as entry element Enzymology.
Topical term or geographic name as entry element Posttranslational Modification.
Topical term or geographic name as entry element Cell Physiology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Conti, Marco.
Relator term editor.
Personal name Houslay, Miles D.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9783642179686
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-642-17969-3
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-05AUM Main Library2014-04-05 2014-04-05 E-Book   AUM Main Library615
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