Etiology -- Narcolepsy: Genetic Predisposition and Pathophysiology -- Animal Models of Narcolepsy: Development, Findings and Perspectives -- Neuroimaging of Narcolepsy -- Clinical Considerations -- Epidemiology of Narcolepsy -- Narcolepsy in Childhood -- Narcolepsy in the Older Adult -- Diurnal and Nocturnal Sleep in Narcolepsy with Cataplexy -- Hypnagogic Hallucinations and Sleep Paralysis -- REM Sleep Behavior Disorder in Narcolepsy with Cataplexy -- Narcolepsy and Other Comorbid Medical Illnesses -- Humor Processing in Human Narcolepsy with Cataplexy -- Dreams in Patients with Narcolepsy -- Psychoanalysis and Narcolepsy -- Symptomatic Narcolepsy or Hypersomnia, with and Without Hypocretin (Orexin) Deficiency -- Hypersomnias Other than Narcolepsy: Differential Diagnosis -- Psychosocial Considerations -- Psychosocial Impact of Narcolepsy in Children and Adolescents -- Quality of Life and Psychosocial Issues in Narcolepsy -- Narcolepsy, Intimacy and Sexuality -- Narcolepsy, Driving and Traffic Safety -- Memory and Cognition in Narcolepsy -- Medico-Legal Aspects of Disability in Narcolepsy -- Narcolepsy and Mental Health -- Management -- Overview of Management of Narcolepsy -- Modes of Action of Drugs Related to Narcolepsy: Pharmacology of Wake-Promoting Compounds and Anticataplectics -- Modafinil/Armodafinil in the Treatment of Narcolepsy -- Sodium Oxybate in the Treatment of Narcolepsy -- Emerging Treatments for Narcolepsy -- Non-pharmacologic Treatments of Narcolepsy.

This interdisciplinary volume brings together many of the world’s leading clinicians and researchers to discuss current and anticipated developments in the understanding of narcolepsy. The volume is broadly divided into four main sections: Section I: Etiology; Section II: Clinical Considerations; Section III: Psychosocial considerations; and Section IV: Management. The areas covered include findings from research investigations on the genetic predisposition and pathophysiology, psychosocial aspects, and clinical management of narcolepsy by means of pharmacological and non-pharmacological methods. Special attention is paid to the translational aspects of narcolepsy. This volume is suitable for sleep disorders specialists and researchers, psychiatrists, neurologists, psychologists, social workers, behavioral scientists, graduate medical students, and any professionals and researchers interested in the interdisciplinary area of sleep medicine. Key Features · Focus on issues faced in day-to-day clinical settings – helps to inform and change clinical practice · Chapters address both clinical and research basis – highlights potential areas of future research · Interdisciplinary and translational approach – suitable for a wide range of clinicians and biomedical professionals Meeta Goswami, BDS, PhD, MPH, has been the director of the Narcolepsy Institute since its inception in 1985 and serves as an Assistant Professor of Neurology, Albert Einstein College of Medicine. Her general area of research interest includes narcolepsy and psychosocial issues. S.R. Pandi-Perumal, M.Sc, is the President and Chief Executive Officer of Somnogen Inc, a New York Corporation. He is a well-recognized sleep researcher both nationally and internationally, and has authored many publications. His general area of research interest includes sleep and biological rhythms. He is a well-known editor in the field of sleep medicine and has edited over 15 volumes dealing with various sleep-related topics. Michael J Thorpy, MD, has won many awards for his research including one of the sleep field's highest honors: the Nathaniel Kleitman Award. He is a well-published researcher and a board-certified sleep physician. He serves as a Professor of Neurology at Albert Einstein College of Medicine and the Director of the Sleep-Wake Disorders Center at Montefiore Medical Center, Bronx, New York.