Chapter 1. The Problem of Cancer Overdiagnosis and Overtreatment -- Chapter 2. Patient Selection for Active Surveillance -- Chapter 3. Predicting High Risk Disease Using Tissue Biomarkers -- Chapter 4. Predicting High Risk Disease Using Serum and DNA Biomarkers -- Chapter 5. Triggers for Intervention in Men on Surveillance -- Chapter 6. The Role of MRI in Active Surveillance -- Chapter 7. Active Surveillance:  The European Experience -- Chapter 8. Active Surveillance:  The Canadian Experience -- Chapter 9. Psychosocial Aspects of Active Surveillance -- Chapter 10. Statistical Considerations for Patient Selection and Triggers for Intervention in Active Surveillance -- Chapter 11. Interpreting PSA Kinetics using GLMM Technique -- Chapter 12. The Potential Benefits of Diet and Physical Activity among Active Surveillance Patients with Low-Burden Prostate Cancer -- Chapter 13. The Role of 5α-Reductase Inhibitors (5-ARIs) in Expectant Management of Low Risk Prostate Cancer -- Chapter 14. Urologists’ Opinion on Active Surveillance: United States vs. the Netherlands -- Chapter 15. Clinical ‘Pearls’ in Managing Patients on Surveillance -- Chapter 16. Active Surveillance, Focal Therapy and the Future -- Chapter 17. The Economics of Active Surveillance for Prostate Cancer -- Chapter 18. The Future of Active Surveillance.

Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management.  The book will also be of interest to scientifically literate patients and their families.   The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehensive guide to the management of patients on surveillance. The volume covers the many complexities and nuances to this approach including, patient selection, risk assessment, how to overcome 'cancer hysteria' when counseling patients, identifying appropriate triggers for intervention, use of PSA kinetics and MR imaging information, technique and frequency of biopsies, secondary prevention interventions, and the relative roles of surveillance and focal therapy.