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Epigenetic Approaches to Allergy Research

by Pascual, Marién.
Authors: Roa, Sergio.%author. | SpringerLink (Online service) Series: SpringerBriefs in Genetics, 2191-5563 Physical details: VIII, 64 p. 13 illus. online resource. ISBN: 1461463661 Subject(s): Medicine. | Human genetics. | Gene expression. | Allergy. | Biomedicine. | Human Genetics. | Gene Expression. | Allergology.
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E-Book E-Book AUM Main Library 611.01816 (Browse Shelf) Not for loan

Introduction -- Immune System and Atopic Disorders -- Epigenetics -- Epigenetics, Environment and Allergic Diseases -- Conclusions and Future Perspectives.

In recent years, epigenetic approaches to existing scientific problems have offered many new and exciting perspectives. This book focuses on epigenetic approaches to study asthma and allergy research. The authors briefly review cellular factors, immune signaling, and inflammatory pathways in allergy and asthma, as well as genetic influences in the pathogenesis of atopic disorders. Diseases that have been clearly linked to an epigenetic dysregulation will be discussed, as well as the role of epigenetics in the origin of complex diseases. The authors will examine the impact of environment factors in the predisposition to atopic disorders, and they will also describe the major unanswered questions and future perspectives of an exciting new field that studies allergic diseases from the epigenetic point of view.       

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