I. Introduction -- Benefits of a translating research on inhibitory control for the prevention drug abuse -- II. Neurobehavioral Approaches for Understanding Inhibitory Control -- Animal models of inhibitory control -- Neurochemical influences on impulsivity and cognitive control in laboratory animals -- Genetic determinants of behavior and impulse control in alcoholic families -- Impaired inhibitory control as a mechanism in drug addiction -- Neuroimaging, adolescence, and risky behavior -- III. Translating Research on Inhibitory Control to At-Risk Populations -- Inhibitory control deficits in childhood and risk for substance use -- Translating basic science research findings into applications for prevention -- Impulsivity and adolescent substance use -- Positive and negative reinforcement processes underlying adolescent risk taking -- Developmental changes in neurocircuitry underlying impulse control and addiction vulnerability in adolescence -- Neurobehavioral disinhibition, brain activation, and risk for substance abuse -- IV. Translating Research on Inhibitory Control to Prevention Interventions -- Effects of adversity on development of inhibitory control and the role of parental involvement on prevention of adverse -- Preventing early conduct problems through a targeted intervention to strengthen inhibitory control and emotional regulation -- Developmental psychopathology: Focusing on core inhibitory competencies to prevent substance abuse -- Designing public service announcements that target impulsive or sensation-seeking adolescents to prevent drug abuse -- Preventive interventions designed to target underlying emotional regulatory mechanisms in high risk behaviors -- V. Conclusion -- Policy issues and advocacy translating research on inhibitory control to drug abuse prevention -- Final thoughts on inhibition and drug abuse: Where do we go from here?.

Inhibitory Control and Drug Abuse Prevention From Research to Translation Michael T. Bardo, Diana H. Fishbein, Richard Milich, editors Some of the most promising findings about drug abuse come from research into behavioral inhibitory control processes—specifically, that individuals with substance use disorders have inhibitory control deficiencies compared to non-abusers, and that the impulsivity associated with adolescence may account for young people’s vulnerability toward drug-taking behavior. But while this neurobiological approach has steadily influenced the treatment of addiction, it has had only minor effect on prevention efforts. Inhibitory Control and Drug Abuse Prevention was compiled to help correct this situation, synthesizing what we know about the neuromechanics of risk-taking, and mining its ample potential in addiction prevention. Noted experts review up-to-date neurobehavioral studies regarding inhibitory control in humans and laboratory animals, discuss their implications for age groups at risk for impulse control deficits or dysfunction, and apply these findings to the development of innovative, effective prevention strategies. Among the topics covered in this multidisciplinary volume: • Genetic and environmental determinants of risk-taking behavior. • Impaired inhibitory control as a mechanism in drug abuse. • Childhood inhibitory control deficits and risk for substance use. • Social influence in inhibitory control. • Translating research into advocacy and policy. • Targeting anti-drug public service messages to sensation-seeking youth. Inhibitory Control and Drug Abuse Prevention represents a sea change in understanding addictive behavior, and is timely reading for researchers and practitioners in the fields of drug abuse (as well as related high-risk behaviors, e.g., delinquency, unsafe sex, gambling), health psychology, and neuropsychology.