Epidemiology of Hepatocellular Carcinoma -- Environmental Carcinogens and Risk for Human Liver Cancer -- Primary Liver Cancer: Chemical Carcinogenesis -- Molecular Mechanisms of Hepatocellular Carcinoma: Insights to Therapy -- Genomic Profiling of Human Hepatocellular Carcinoma -- Pathologic Aspects of Hepatocellular Tumors -- Hepatocellular Carcinoma Associated with Hepatitis B Virus -- Hepatitis C and Hepatocellular Carcinoma -- Metabolic Disease and Hepatocellular Carcinoma -- Clinical Features and a Clinician’s Diagnostic Approach to Hepatocellular Carcinoma -- Screening and Biomarkers for Hepatocellular Carcinoma -- Use of Imaging Techniques to Screen for Hepatocellular Carcinoma -- MRI for Detection and Evaluation of Hepatocellular Carcinoma -- Ultrasound of Hepatocellular Carcinoma: The Important Contribution of Contrast Enhancement -- Percutaneous Ethanol Injection -- Radiofrequency Ablation of Hepatocellular Carcinoma -- Resection of Hepatocellular Carcinoma -- Liver Transplantation for Hepatocellular Carcinoma -- Living Donor Liver Transplantation for Hepatocellular Carcinoma -- Medical Therapy of HCC -- Percutaneous Interventional Technique for Intra-arterial Chemoembolization -- Molecular Targeted Therapies for HCC -- Radiation Therapy for Hepatocellular Carcinoma -- Psychosocial Issues in Hepatocellular Carcinoma -- Putting It All Together.

Hepatocellular cancer is the the fifth most common cancer, with 600,000 new cases reported each year worldwide. Additionally, exciting changes in the science of HCC in the last four years have turned the practice of diagnosing and treating the disease upside down. In Hepatocellular Carcinoma: Diagnosis and Treatment, Second Edition, the leading experts in the field of HCC thoroughly update and expand upon the critically acclaimed first edition with all the latest developments in the diagnosis and treatment of primary liver cancer. The book details for physicians the diagnostic and therapeutic decision making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. New chapters discuss the introduction into clinical practice of cell cycle growth inhibitors, an expanded knowledge of Genomics and Proteomics, and novel ways of delivering intra-hepatic chemotherapy. This cutting-edge text is a vital resource and must have for today’s hepatologists and medical and surgical oncologists.