Defining the Disease -- Historical Aspects -- Epidemiology, Definitions and Classification -- Histopathology -- Generalized Vitiligo -- Segmental Vitiligo -- Vitiligo Universalis -- Mucosal Vitiligo -- Halo Nevi and Vitiligo -- Hair Involvement in Vitiligo -- Non-Skin Melanocytes in Vitiligo -- Autoimmune/Inflammatory and Other Diseases Associated with Vitiligo -- Vitiligo and Immunodeficiencies -- Inflammatory Vitiligo -- Rare Inherited Diseases and Vitiligo -- Vitiligo in Childhood -- Late-Onset Vitiligo -- Evaluation, Assessment and Scoring -- Quality of Life -- Natural History and Prognosis -- Defining the Disease: Editor's Synthesis -- Understanding the Disease -- Pathophysiology Overview -- Genetics -- Environmental Factors -- In Vivo Data -- Animal Models -- In Vitro Approaches -- Oxidative Stress -- Immune/Inflammatory Aspects -- Cytokines and Growth Factors -- Proopiomelanocortin and Related Hormones -- Other Hypotheses -- Particular Clinical Characteristics of Segmental Vitiligo -- The Concept of Mosaicism Applied to SV -- The Neurogenic Hypothesis in Segmental Vitiligo -- Segmental Vitiligo: A Model for Understanding the Recapitulation of Repigmentation -- Editor’s Synthesis -- Therapy -- Management Overview -- Topical Corticosteroids -- Calcineurin Inhibitors -- Vitamin D Analogues -- PUVA and Related Treatments -- UVB Total Body and Targeted Phototherapies -- Vitamins and Antioxidants: Topical and Systemic -- Corticosteroid Minipulses -- Other Immunosuppressive Regimen -- Empirical, Traditional, and Alternative Treatments -- Background and Techniques -- The Outcomes: Lessons About Surgical Therapy for Vitiligo in the Past Two Decades -- Combined Therapies for Vitiligo -- Camouflage -- Photoprotection Issues -- Depigmenting Agents -- Therapy Adapted for Age, Gender, and Specific Locations -- Psychological Interventions -- The Patient Perspective -- Evidence-Based Medicine Perspective -- Editor's Synthesis and Perspectives.

Vitiligo is one of the most common cutaneous disorders. Great numbers of affected patients suffer from the high stigmatizing impact of this disease. Up to now, clinical guidelines for the treatment of vitiligo were non-existent. In order to fill this void, this textbook defines and gives a complete overview of the disease, both regarding the classification of differential diagnosis as well as the treatment. Written by the most authoritative experts in the field, all therapy recommendations are based on new evidence-based guidelines. It includes case studies with illustrations before and after the treatment in order to demonstrate the treatment success. This textbook will be a valuable resource for all physicians who are seeing patients with this disease.