Collaboration Networks for Innovation and Socio-economic Development: European and Latin American Perspectives on Digital Ecosystems Research, Local Readiness, Deployment Strategies and Their Policy Implications -- Exploring the Role of Value Networks for Software Innovation -- Social Network Analysis of the Irish Biotech Industry: Implications for Digital Ecosystems -- Digital Ecosystem for Knowledge, Learning and Exchange: Exploring Socio-technical Concepts and Adoption -- The Diffusion of Social Media and Knowledge Management – Towards an Integrative Typology -- Digital Ecosystems Adoption at Local Level: A Preliminary Comparative Analysis -- The Role of the Region in Knowledge Transfer for Economic Development -- Fostering Social Technologies Sharing through Open Knowledge Space: A Brazilian Case Study of Knowledge Network -- Analysing Collaboration in OPAALS’ Wiki: A Comparative Study among Collaboration Networks -- Towards the Complex Interface -- Knowledge Resources – A Knowledge Management Approach for Digital Ecosystems -- Launching Context-Aware Visualisations -- A Practical Approach to Identity on Digital Ecosystems Using Claim Verification and Trust -- Implementing a Trust Overlay Framework for Digital Ecosystems -- SPAM Detection Server Model Inspired by the Dionaea Muscipula Closure Mechanism: An Alternative Approach for Natural Computing Challenges -- Towards Autopoietic Computing -- Flypeer: A JXTA Implementation of DE Transactions -- A Research Framework for Interaction Computing -- Transformation Semigroups as Constructive Dynamical Spaces -- Numerical and Experimental Analysis of the p53-mdm2 Regulatory Pathway -- Lie Group Analysis of a p53-mdm2 ODE Model.

This book constitutes the thoroughly refereed post-conference proceedings of the Third International Conference on Digital Eco-Systems, OPAALS 2010, held in Aracajú, Sergipe, Brazil in March 2010. The papers cover topics from Social Science, Computer Science and from Natural Science. These include social networks, social technologies, digital ecosystems, knowledge management, context-aware situation and digital ecosystems, Lie group analysis, constructive dynamical spaces, and interaction computing.