Arsenic-Based Drugs: From Fowler’s Solution to Modern Anticancer Chemotherapy -- Activation Mechanisms for Organometallic Anticancer Complexes -- Organometallic Antitumour Agents with Alternative Modes of Action -- Ferrocene Functionalized Endocrine Modulators as Anticancer Agents -- Titanocenes: Cytotoxic and Anti-angiogenic Chemotherapy Against Advanced Renal-Cell Cancer -- Organometallics as Structural Scaffolds for Enzyme Inhibitor Design -- Bioorganometallic Chemistry and Malaria -- Biomedical Applications of Organometal–Peptide Conjugates -- Organometallic Radiopharmaceuticals -- Carbon Monoxide: An Essential Signalling Molecule.

Contents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler’s solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes – Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide – an essential signaling molecule.