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Bioinformatics for Immunomics

by Flower, Darren D.R.
Authors: Davies, Matthew.%editor. | Ranganathan, Shoba.%editor. | SpringerLink (Online service) Series: Immunomics Reviews:, An Official Publication of the International Immunomics Society ; . 3 Physical details: XVI, 192 p. online resource. ISBN: 1441905405 Subject(s): Medicine. | Human genetics. | Immunology. | Bioinformatics. | Microbiology. | Biomedicine. | Immunology. | Bioinformatics. | Microbiology. | Human Genetics.
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E-Book E-Book AUM Main Library 616.079 (Browse Shelf) Not for loan

Computational Vaccinology -- The Immuno Polymorphism Database -- The IMGT/HLA Database -- Ontology Development for the Immune Epitope Database -- TEPIDAS: A DAS Server for Integrating T-Cell Epitope Annotations -- Databases and Web-Based Tools for Innate Immunity -- Structural Immunoinformatics: Understanding MHC-Peptide-TR Binding -- Discovery of Conserved Epitopes Through Sequence Variability Analyses -- Tunable Detectors for Artificial Immune Systems: From Model to Algorithm -- Defining the Elusive Molecular Self -- A Bioinformatic Platform for a Bayesian, Multiphased, Multilevel Analysis in Immunogenomics.

The field of Immunomics has developed within the post-genomic era as a response to the massive amount of biological and immunological data now available to researchers. Immunomics crosses the disciplines of immunology, genomics, proteomics and computational biology and address some fundamental problems in biological and medical research. This book covers some of the rich sources of immunological data that are currently available and describes the various bioinformatics techniques that have been utilized to aid our understanding of the immune system. It also describes the nature of the self/non-self distinction that forms the basis of immunological theory and how computational modeling can help to clarify our understanding of how the immune system works.

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