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Fine Particles in Medicine and Pharmacy

by Matijević, Egon.
Authors: SpringerLink (Online service) Physical details: XIII, 348p. 168 illus., 74 illus. in color. online resource. ISBN: 1461403790 Subject(s): Chemistry. | Analytical biochemistry. | Biotechnology. | Chemical engineering. | Biochemistry. | Pharmacy. | Chemistry. | Biotechnology. | Medicinal Chemistry. | Industrial Chemistry/Chemical Engineering. | Surface and Interface Science, Thin Films. | Pharmacy. | Analytical Chemistry.
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E-Book E-Book AUM Main Library 660.6 (Browse Shelf) Not for loan

Models of Size and Shape Control in Synthesis of Uniform Colloids and Nanocrystals -- Preparation of Uniform Drug Particles -- Biomedical Applications of Metal Oxides -- Biomedical Applications of Gold Nanoparticles -- Biomedical Applications of Magnetic Particles -- Degradable Polymer Particles for Biomedical Applications -- Functionalization of Inorganic Nanoparticles for Targeted Delivery -- Particle Deposition in the Human Respiratory Tract -- Detection of Oxidative Stress Biomarkers Using Functional Gold -- Stimuli-responsive Thin Films and Capsules: Approaching Smart Drug Delivery Systems -- Medicine in Reverse: Colloidal Technology for Combating Chemical Overdoses.

Pharmaceutical manufacture is very exacting – for example, drugs must be uniform in size, shape, efficacy, bioavailability, and safety. The presence of different polymorphs in drug production is a serious problem, since different polymorphs differ in bioavailability, solubility, dissolution rate, chemical and physical stability, melting point, color, filterability, density, and flow properties. Fine Particles in Medicine and Pharmacy discusses particle size, shape, and composition and how they determine the choice of polymorph of a drug.

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