Introduction -- Joint replacements - historical overview -- Biomaterials in artificial joint replacements -- The definition of prosthetic joint infections (PJIs) -- Classifications of prosthetic joint infections -- The epidemiology of total joint arthroplasty infections -- Septic complications in arthroplasty -- Perioperative antibiotic prophylaxis in total joint arthroplasty -- Risk factors for prosthetic joint infections -- Pathogenesis of prosthetic joint infections -- Bacteria-biomaterial interactions -- Biomaterial-host interactions in aseptic and septic conditions -- Influence of wear particles on local and systemic immune system -- Diagnostic evaluations -- Sinovial fluid cytology -- Histological analysis of periprosthetic tissue for detecting prosthetic joint infection -- Microbiological diagnosis of  prosthetic joint infection -- Microbiological processing of samples in the investigation of suspected prosthetic joint infections -- Molecular diagnosis of prosthetic joint infection -- Current treatment strategies in prosthetic joint infections -- Total ankle replacement infections -- Periprosthetic Infection Issues With Osseointegrated (OI) Implant Technology in Amputees -- The algorithm for diagnostic evaluation and treatment -- Bone grafts and bone graft substitutes in infected arthroplasty -- Pitfalls of antimicrobial therapy in infected joint artroplasty.

There are a variety of protocols that are used in infected total joint arthroplasty. This book will outline and detail the best possible course of treatment and formulate custom algorithms for every possible case, based on current evidence. reviews of current concepts  and “recipes” for the diagnostic and therapeutic procedures (surgical and antibiotic) based on the type of implant, infection and the patient.   The book will be an essential resource on infected total joint arthroplasty, containing a series of logical and highly detailed instructions that will serve to educate orthopedic surgeons operating in this field on the best approaches, according to detailed and careful research conducted over the last decade.