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Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology /

Authors: Han, Chao.%editor | Davis, Charles B.%(Charles Baldwin)%editor | %Wang, Binghe,%PhD.%editor Series: Wiley series in drug discovery and development Published by : Wiley, (Hoboken, N.J. :) Physical details: x, 289 p., [2] p. of plates : ill. (some col.) ; 25 cm. ISBN: 0470044918 Subject(s): Drug development. | Pharmacokinetics. | Drugs %Metabolism. | Drug Evaluation, Preclinical. | Drug Discovery. | Drug Industry %standards. | Pharmaceutical Preparations %metabolism. | Pharmacology %methods. Year: 2010
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Item type Location Call Number Status Date Due
Book Book AUM Main Library 615.19 E93 (Browse Shelf) Available
Book Book AUM Main Library 615.19 E93 (Browse Shelf) Available

Includes bibliographical references and index.

Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown.

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